Kira is going to have a busy and fun summer chasing down information about this Gene at the Mayo Clinic in Rochester, MN this summer. This sounds like a very fun and challenging summer for our girl. Congrats on your Internship Kira!How Shh Got its Name--Sonic hedgehog is, in fact, named after the character from the popular Sega Genesis video game. The original hedgehog gene was found in Drosophila and was named for the appearance of the mutant phenotype which causes an embryo to be covered with pointy denticles resembling a hedgehog. The first two homologues of hedgehog were named after species of hedgehog and the third was named after the video game character (Gilbert, 2000).
What is Sonic Hedgehog?
Sonic Hedgehog is one of three homologues found in vertebrates. The hedgehog family consists of sonic hedgehog (shh), desert hedgehog (dhh), and indian hedgehog (ihh). Shh is the most common of the three and is therefore the best documented (Gilbert, 2000). Shh is made in the notochord of developing embryos. This important protein has many functions throughout the life of the organisms in which it is expressed. http://images.google.com/imgres?imgurl=http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/Watson/shh1.jpg&imgrefurl=http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/Watson/Sonichedgehog.htm&usg=__Ud7LkOlyLgM9m2D-zxRb0OZ3LGI=&h=350&w=337&sz=36&hl=en&start=1&um=1&tbnid=fsmGtV4VwvllkM:&tbnh=120&tbnw=116&prev=/images%3Fq%3Dsonic%2Bhedgehog%2Bgene%26hl%3Den%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7GFRD%26sa%3DN%26um%3D1http://.
What is Sonic Hedgehog?
Sonic Hedgehog is one of three homologues found in vertebrates. The hedgehog family consists of sonic hedgehog (shh), desert hedgehog (dhh), and indian hedgehog (ihh). Shh is the most common of the three and is therefore the best documented (Gilbert, 2000). Shh is made in the notochord of developing embryos. This important protein has many functions throughout the life of the organisms in which it is expressed. http://images.google.com/imgres?imgurl=http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/Watson/shh1.jpg&imgrefurl=http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/Watson/Sonichedgehog.htm&usg=__Ud7LkOlyLgM9m2D-zxRb0OZ3LGI=&h=350&w=337&sz=36&hl=en&start=1&um=1&tbnid=fsmGtV4VwvllkM:&tbnh=120&tbnw=116&prev=/images%3Fq%3Dsonic%2Bhedgehog%2Bgene%26hl%3Den%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7GFRD%26sa%3DN%26um%3D1http://.
